New avenues to prevent heart disease.

Date: 20/02/2021

Source: https://www.sciencedaily.com

Summary: A professor of biomedical sciences has developed a better knowhow of the medical characteristics behind heart disease and the scope for it's prevention.


Entire Coverage- 
Almost 5 lacs citizens die by SCD- sudden heart attack in the United States in a year due to break down in heart functioning.

A leading cause of SCD- sudden cardiac death, in young sportsperson is Arrhythmogenic Cardiomyopathy (ACM),  a genetic which is in fact an ailment in which heart muscle is restored with time by fibrosis and fat.

An assistant professor Stephen Chelko, at the Florida State University College of Medicine, has evolved a better apprehension of the pathological traits following the ailment, as well as genuine opportunities for prevention and cure His discoveries are published in the current section of Science Translational Medicine.

People with ACM have a mutation causing arrhythmias, those are harmless if treated effectively.Nonetheless, he exhibits that training not only amplifies those arrhythmias, but catalyses wide cell expiration. The avenue left is to cease participating in exercise.

"There is an irony in that exercise, a known health benefit for the heart, leads to cell death in ACM probables," Chelko said. "Now, we know that exercise, leads to widespread myocyte cell expiration due to mitochondrial dysfunction in those who suffer from this genetic heart disease.

He discovered that cell expiration can be stopped by inculcating two different proteins. One such approach utilizes a novel targeting peptide developed for Chelko's research by the National Research Council in Padova, Italy.

This research opens up opportunities for the development of new options to prevent myocyte cell death, cardiac dysfunction and the pathological progression leading to deadly consequences for people living with ACM.


Article Source:

Materials provided by Florida State University. Original written by Doug Carlson.

 Note: Content may be edited for style and length and avoid repetition.


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